Personalized Nutrition: Insights from the PREDICT 1 Study

The PREDICT 1 study, involving 1,002 UK adults, highlights the significant variability in individual metabolic responses to identical meals. Factors like gut microbiome influenced postprandial triglyceride levels more than meal macronutrients, whereas glycemic responses were more affected by meal composition. Genetic impact was modest. Machine-learning models predicted metabolic responses effectively, supporting the development of personalized dietary strategies. This research underscores the importance of tailored nutrition plans to address individual metabolic differences, potentially improving health outcomes and preventing diet-related diseases.