The Information Theory of Aging

A recent perspective in Nature Aging introduces the "Information Theory of Aging" (ITOA), proposing that aging results from the gradual loss of youthful epigenetic information. While the genome provides a stable blueprint for life, the more fluid epigenome is vulnerable to environmental and cellular damage over time. The theory suggests that aging could be reversed by reprogramming epigenetic markers, potentially restoring function in aged or damaged tissues. This new paradigm opens possibilities for novel therapeutic strategies aimed at rejuvenation and longevity.