mosGraphGen: Facilitating Multi-Omics Analysis with Graph AI

Typeresearch
AreaAICompBio
Published(YearMonth)2410
Sourcehttps://academic.oup.com/bioinformaticsadvances/advance-article/doi/10.1093/bioadv/vbae151/7815723?searchresult=1
Tagnewsletter
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The newly developed tool, mosGraphGen, generates biologically meaningful multi-omics signaling graphs (mos-graphs) by integrating and normalizing multi-omics data. This tool allows researchers to map complex genomic, epigenomic, transcriptomic, and proteomic datasets onto signaling networks, enhancing their use in graph AI models. By providing pre-analyzed graphs, mosGraphGen simplifies model development and interpretation. Demonstrated with data from The Cancer Genome Atlas and Alzheimer’s disease studies, mosGraphGen proves to be a powerful resource for advancing integrative multi-omics research.