scGHOST: Mapping the 3D Genome Landscape
| Type | research |
|---|---|
| Area | CompBio |
| Published(YearMonth) | 2404 |
| Source | https://www.nature.com/articles/s41592-024-02230-9 |
| Tag | newsletter |
| Checkbox | |
| Date(of entry) |
The research detailed in Nature Methods introduces scGHOST, a novel method for annotating single-cell 3D genome subcompartments using graph embedding techniques. scGHOST enhances the understanding of genome organization by identifying specific nuclear subcompartments in single cells, linking these to gene transcription across various cell types and developmental stages. This breakthrough offers new perspectives on cellular variability and genome functionality.